INTERNATIONAL JOURNAL OF ADVANCE RESEARCH
IN MULTIDISCIPLINARY

Background: Angina pectoris, characterized by chest pain or discomfort, poses a significant health burden, especially in the elderly population. This retrospective cohort study aimed to analyze 100 cases of angina pectoris in a tertiary care hospital, focusing on risk factors and medication patterns.

Methods: It is a retrospective cohort study. Data were collected over six months in a tertiary care hospital, including patient demographics, angina types, and associated risk factors. Statistical analysis was conducted to identify patterns and trends in drug utilization.

Results: The study revealed a male predilection (73%) with the majority in the 61-70 age group (40%). Stable angina was prevalent (75%), and hypertension (61%) emerged as the primary risk factor, followed by high cholesterol (50%) and diabetes (45%). Smoking and alcohol intake were reported in 23% and 24% of cases, respectively. Most patients (98%) exhibited two or more risk factors. Antiplatelet therapy, predominantly Clopidogrel (89%) and Aspirin (87%), was common. Atenolol (79%), Amlodipine (83%), and Isosorbide dinitrate (82%) were prevalent among prescribed drugs. Dual antiplatelet therapy (Clopidogrel + Aspirin) was notable in 78% of cases.

Conclusion: The study underscores the predominance of stable angina, male gender as a significant risk factor, and a high prevalence of comorbidities. Antiplatelet therapy, especially dual therapy, emerged as a key pharmacological intervention. Addressing lifestyle factors and implementing preventive measures are crucial to mitigate the rising incidence of angina in the population.