INTERNATIONAL JOURNAL OF ADVANCE RESEARCH
IN MULTIDISCIPLINARY

A major public health problem nowadays is the evolution of antimicrobial medication resistance on a global scale. Decades of study have not eliminated the devastating impact of bacterial illnesses on human health. These include TB, septicaemia, staphylococcal skin infections, pneumonia, and others. Microbes resistant to many regularly used antibiotics have emerged as a result of the overuse and misuse of antibiotics in recent decades, which might make future infections very challenging to cure. Due to the widespread medication resistance and, in particular, the appearance of their multidrug-resistant phenotypes, the management of these illnesses continues to be a significant issue in modern times. This highlights the critical need for new classes of antimicrobials that can effectively combat multidrug-resistant bacteria. Our findings provide light on the eternal possibilities of bacteria in this area, which is quite encouraging. The latest research confirms that uncommon actinomycetes might be a great source of new antimicrobial agents that effectively inhibit the development of many multidrug-resistant bacteria. Our research leads us to believe that uncommon actinomycetes and the bioactive metabolites they produce might be a viable alternative to conventional antibiotics in the fight against multidrug-resistant bacteria. Research into the use of microbial natural products in the pharmaceutical industry has a promising future.