INTERNATIONAL JOURNAL OF ADVANCE RESEARCH
IN MULTIDISCIPLINARY

This study establishes a cross-disciplinary conceptual framework by evaluating fungal multi-mycotoxin contamination through the lens of Indian Knowledge Systems (IKS), specifically utilizing the Ayurvedic toxicological model of Dushi Visha (latent, cumulative xenobiotic toxicity). By biochemically aligning contemporary low-dose, multi-mycotoxin profiles with the classical principles of Alpa-veerya (attenuated potency) and Sthayee (environmental and tissue persistence), this paper redefines the pathophysiology of chronic dietary mycotoxicosis. Furthermore, we propose an integrated mitigation paradigm that synthesizes high-throughput analytical protocols-specifically Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)-with traditional post-harvest agronomic interventions and Agada Tantra (traditional toxicological) detoxification methodologies to neutralize bioaccumulative fungal metabolites.