Vaastu Shastra is an ancient Indian system based on building principles. It is thought that natural ventilation utilizes the natural forces of wind and buoyancy to bring air in and out of the building to maintain interior temperatures at comfortable levels. Despite being perceived traditionally, Vaastu Shastra helps in the creation of a healthy and comfortable living condition and may also carry some scientific validity. The article discusses the basic elements of Vaastu Shastra and natural ventilation, emphasizing the possible alignment between them. The study will clarify how natural strategies in Vaastu objectives for window location, space placement, and courtyard design can help improve natural ventilation or sustainable ventilation strategies that improve the quality of indoor air and airflow in a building. The paper highlights the limitations of the existing research conducted in terms of scientific certification of Vaastu Siddhi Principles. However, it recommends further analysis to recognize the link between traditional knowledge and new configurations in science.